Latest in ADCs
Latest
New CAR-T Manufacturing Method Uses Multi-Cytokine Scaffold to Improve T Cell Persistence
EXCERPT: Researchers have published an alternative CAR-T manufacturing approach using a protein scaffold linking IL-7, IL-15, and IL-21. The resulting cells show improved survival, maintained effector function, and self-renewal capacity
ADCs
AAV Contaminants Found in Liver Biopsy After Gene Therapy Infusion — A Manufacturing Wake-Up Call
EXCERPT: A Nature Medicine study found manufacturing plasmid sequences and incomplete helper virus genomes in liver tissue from a patient who developed acute liver failure after AAV therapy. The implications